Product shot of Aspercreme® Arthritis gel


Aspercreme® Arthritis Pain Relief Gel makes prescription-strength diclofenac available over the counter.

To ease joint pain, just apply Aspercreme® Arthritis topical diclofenac gel directly to your hands, wrists, elbows, feet, ankles, or knees. It’s clinically proven to relieve arthritis pain, and can help reduce stiffness and improve mobility.

On This Page You Will Learn About:

What Is Diclofenac?

Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) that has been used by US patients and doctors for more than 10 years. When applied topically, diclofenac gel has demonstrated efficacy in treating arthritis,1 including osteoarthritis, the most common type of arthritis.2 

It works by inhibiting the production of prostaglandins, which are the substances that control inflammation in the body.3

Arthritis sufferers are all too familiar with the painful joints that come with inflammation, and how hard it can be to move. Topical diclofenac helps relieve pain and alleviate stiffness by diminishing inflammation

Until recently, diclofenac was only available with a prescription. But now with Aspercreme® Arthritis Pain Relief Gel, you can get this highly effective NSAID over the counter.

How Aspercreme® Arthritis Can Help

Aspercreme® Arthritis was formulated with one thing in mind: to help you enjoy everyday activities without arthritis pain. You can do the dishes, work in the garden, or play with the dog — all without worrying about aching joints. 

Aspercreme® Arthritis is designed for topical application to treat arthritis pain. When applied and used as directed, it can provide lasting relief from pain due to arthritis.

The Convenience Of A Gel

Get where-you-need-it relief from pain in the hands, wrists, elbows, feet, ankles, and knees. 

Unlike pills, Aspercreme® Arthritis is applied directly to the joint, so you get pain relief directly at the source. The gel formula is non-greasy. And because it has the active ingredient diclofenac, Aspercreme® Arthritis provides targeted OTC pain relief that was previously only available with a prescription.

Learn How To Treat Pain

Many topical agents contain ingredients that can offset the pain in underlying muscles or joints by creating a sensation of cooling or warmth4 that really just irritates the skin.

Aspercreme® Arthritis gel with diclofenac can treat the pain when used as directed. It penetrates below the skin to reduce inflammation.4 Aspercreme® Arthritis has demonstrated the ability to treat arthritis pain when applied topically. 

And if you’re wondering about the correct pronunciation of the active ingredient, our sources tell us it’s die-KLOH-fuh-nack.

You’re welcome!

Aspercreme® Arthritis Topical Gel — Rx-strength Relief, Available Otc

Take a walk in the park. Make dinner. Work in the garden. All without pain getting in the way. 

Don’t let pain get in your way. Aspercreme® Arthritis is a new topical gel with diclofenac. This prescription-strength pain reliever is now available over the counter.

Don’t just mask arthritis pain. Treat arthritis pain.



1. Zacher J, et al. Topical diclofenac and its role in pain and inflammation: an evidence-based review. Curr Med Res Opin 2008;24:925–50.

2.  Arthritis Foundation, Osteoarthritis,

3. Mathews P, Derry S, et al. Topical rubefacients for acute and chronic pain in adults, National Center for Biotechnology Information (, July 8, 2009.

4. Derry S, et al. Salicylate-containing rubefacients for acute and chronic musculoskeletal pain in adults (Review). Cochrane Database Syst Rev 2014: CD007403.